Much worry dries out and withers the physical brain. Worried thoughts make furrows in it and thereby make one think such thoughts repeatedly. Here the physical body becomes a hindrance to a man’s progress. Facial wrinkles reflect these groove[s]. Worries live in a certain astral substance; soters [sic] are highly developed individualities who take this sorrow substance upon themselves. The greatest man of sorrow was Christ.
Source: Rudolf Steiner – GA 266 – From the Contents of Esoteric Classes – Berlin, 11th November 1908